项目作者: TalSchuster

项目描述 :
Simple python retriever for Biorxiv articles
高级语言: Python
项目地址: git://github.com/TalSchuster/BiorxivRetriever.git
创建时间: 2020-05-13T00:33:19Z
项目社区:https://github.com/TalSchuster/BiorxivRetriever

开源协议:MIT License

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BiorxivRetriever

Simple python retriever for BioRxiv articles.

Wraps HTTP requests. Follow the guidelines and policies of BioRxiv.

Purpose

Given a text query, search for relevant papers on BioRxiv and get their links and content.

Install

Install with pip:

  1. pip install biorxiv_retriever

Alternatively, clone this repo and install:

  1. git clone https://github.com/TalSchuster/BiorxivRetriever.git
  2. python setup.py install

API

  1. from biorxiv_retriever import BiorxivRetriever
  2. br = BiorxivRetriever()
  3. papers = br.query('covid remdesivir')

To get only titles and links without metadata and full text (when possible):

  1. papers = br.query('covid remdesivir', metadata=False, full_text=False)

To use Rxivist as the search engine (provides extra metadata but doesn’t have all papers):

  1. br = BiorxivRetriever(search_engine='rxivist')

Output

Example output:

  1. [
  2. {'title': 'Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases',
  3. 'biorxiv_url': 'https://www.biorxiv.org//content/10.1101/2020.04.21.053017v2',
  4. 'posted': 'May 11, 2020.',
  5. 'abstract': 'Abstract Influenza A virus and coronavirus strains cause a mild to severe respiratory disease that can result in death. Although vaccines exist against circulating influenza A viruses, such vaccines are ineffective against emerging pandemic influenza A viruses. Currently, no vaccine exists against coronavirus infections, including pandemic SARS-CoV-2, the causative agent of the Coronavirus Disease 2019 (COVID-19). To combat these RNA virus infections, alternative antiviral strategies are needed. A key drug target is the viral RNA polymerase, which is responsible for viral RNA synthesis. In January 2020, the World Health Organisation identified enisamium as a candidate therapeutic against SARS-CoV-2. Enisamium is an isonicotinic acid derivative that is an inhibitor of multiple influenza B and A virus strains in cell culture and clinically approved in 11 countries. Here we show using in vitro assays that enisamium and its putative metabolite, VR17-04, inhibit the activity of the influenza virus and the SARS-CoV-2 RNA polymerase. VR17-04 displays similar efficacy against the SARS-CoV-2 RNA polymerase as the nucleotide analogue remdesivir triphosphate. These results suggest that enisamium is a broad-spectrum small molecule inhibitor of RNA virus RNA synthesis, and implicate it as a possible therapeutic option for treating SARS-CoV-2 infection. Unlike remdesivir, enisamium does not require intravenous administration which may be advantageous for the development of COVID-19 treatments outside a hospital setting.',
  6. 'full_text': '...'}
  7. ]